Improved biochemical preparation ofL-kynurenine
نویسندگان
چکیده
منابع مشابه
Biochemical and phenotypic abnormalities in kynurenine aminotransferase II-deficient mice.
Kynurenic acid (KYNA) can act as an endogenous modulator of excitatory neurotransmission and has been implicated in the pathogenesis of several neurological and psychiatric diseases. To evaluate its role in the brain, we disrupted the murine gene for kynurenine aminotransferase II (KAT II), the principal enzyme responsible for the synthesis of KYNA in the rat brain. mKat-2(-/-) mice showed no d...
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KFase (kynurenine formamidase), also known as arylformamidase and formylkynurenine formamidase, efficiently catalyses the hydrolysis of NFK (N-formyl-L-kynurenine) to kynurenine. KFase is the second enzyme in the kynurenine pathway of tryptophan metabolism. A number of intermediates formed in the kynurenine pathway are biologically active and implicated in an assortment of medical conditions, i...
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ژورنال
عنوان ژورنال: Experientia
سال: 1974
ISSN: 0014-4754,1420-9071
DOI: 10.1007/bf01934854